Olivier Tillement

This paper develops a hydrogel that enables subcutaneous delivery of vesicant antibody-drug conjugates by confining them in a depot, reducing tissue damage while maintaining antitumor efficacy.

This study evaluates the effects of nanomaterials on human immune cells, finding that PLGA NPs enhance NK cell function while Si-Gd NPs impair T cell activation.

This study shows that AGuIX nanoparticles and their combination with ionizing radiation induce proinflammatory reprogramming of tumor-associated macrophages via AMPK-dependent mitochondrial fragmentation.

This paper demonstrates that combining radiation with gold nanoparticles enhances tumor vascular permeability and improves nanodrug delivery in pancreatic cancer.