Xin Gu

This study identifies INSM1 as a key regulator of neuroendocrine plasticity and tumor progression in prostate cancer, showing its role in lineage programs and identifying HHT as a potential therapeutic agent.

This study shows that inhibiting glucosylceramide synthase (GCS) re-sensitizes drug-resistant cancer cells with homozygous p53 mutations to chemotherapy and reduces cancer stem cells.

This study examines PKM1 and PKM2 expression in mouse and human prostatic tissues across development, benign, and cancerous states, revealing distinct patterns in PCa and NEPCa.