MicrobiologyACS Infectious DiseasesPeer-reviewed
Bacterial Aminopeptidase-Activated Peptide Prodrug Enables Species-Selective Targeting of Pseudomonas aeruginosa
Qingtian Gong, Silvia A. Synowsky, Aisling Lynch…·Clarissa Melo Czekster
This paper designs and tests aminopeptidase-activated AMP prodrugs that selectively target Pseudomonas aeruginosa, showing improved antimicrobial activity and reduced cross-resistance.
DOI 10.1021/acsinfecdis.6c00281