Author

L. Nicolas Gonzalez Castro

Broad InstituteORCID 0000-0001-7699-5188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Mario L. SuvàiD· 2 shared Alex K. ShalekiD· 1 shared Alissa GreenwaldiD· 1 shared Andrew N. Chiocca· 1 shared Angelica Brooke Patterson· 1 shared B. E. BernsteiniD· 1 shared Chadi A. El FarraniD· 1 shared Charles CouturieriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Mario L. SuvàORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 13, 2026

Spatial analysis reveals the evolving organization of low-grade and high-grade IDH-mutant glioma

Rouven Hoefflin, Alissa Greenwald, Noam Galili Darnell…·Itay Tirosh

This study uses spatial transcriptomics and proteomics to analyze IDH-mutant gliomas, revealing distinct spatial organization patterns across tumor grades.

DOI 10.64898/2026.03.12.709536

humanspatial transcriptomics

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Cancer BiologyNaturePeer-reviewedFeb 26, 2025

Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas

Tyler E. Miller, Chadi A. El Farran, Charles Couturier…·B. E. Bernstein

The paper identifies four immunomodulatory programs in glioma-associated myeloid cells using scRNA-seq and shows they are driven by microenvironmental cues and therapies, not cell type or mutation status.

190 citationstop 1%

humanscRNA-seq

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