BiochemistryMolecular Therapy — Nucleic AcidsPeer-reviewed
uORF-targeting steric block antisense oligonucleotides do not reproducibly activate RNASEH1 expression
Nina Ahlskog, Nenad Svrzikapa, Rushdie Abuhamdah…·Thomas C. Roberts
The paper tests uORF-targeting ASOs for RNASEH1 upregulation but finds no reproducible activation, instead observing downregulation in some cases.
14 citations