Author
Bioinformatics Core Facility, Institut Imagine-Structure Fédérative de Recherche Necker, INSERM U1163ORCID 0000-0001-7870-7821Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Georgia Malamut, Nicolas Guégan, Francesco Carbone…·Anaïs Levescot
This study identifies clonal lymphocyte expansions and JAK-STAT mutations in celiac disease subtypes, revealing shared mechanisms and limitations of JAK inhibitor therapy.
Giulia Hardouin, Pierre Martinucci, Samantha Scaramuzza…·Annarita Miccio
Preclinical safety and efficacy studies of a new gene therapy approach for patients with severe β-hemoglobinopathies.
Simon Perrin, Maria Ethel, Vincent Bretegnier…·Céline Colnot
The paper uses single-nuclei transcriptomics to map periosteal skeletal stem/progenitor cell differentiation during bone regeneration, identifying injury-induced fibrogenic cells and their role in osteogenesis and chondrogenesis.
Mégane Brusson, Anne Chalumeau, Pierre Martinucci…·Annarita Miccio
This study develops a bifunctional lentiviral vector for sickle cell disease that combines gene addition and gene silencing to reduce HbS levels and improve treatment efficacy.