Author

David L. Jaye

Emory UniversityORCID 0000-0001-7977-6909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ajay K. NookaiD· 2 shared Sagar LonialiD· 2 shared Alden Staub· 1 shared Alessandro LaganàiD· 1 shared Benjamin G. BarwickiD· 1 shared Bruce A. RosaiD· 1 shared Cem GabayiD· 1 shared Craig C. HofmeisteriD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

Ajay K. NookaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 25, 2026

Spatial multi-omics of multiple myeloma uncovers niche-dependent pro-myeloma and immunosuppressive signaling in the bone marrow and extramedullary lesions

Denis J. Ohlstrom, Marina E. Michaud, Mojtaba Bakhtiari…·Manoj Bhasin

This study uses spatial and single-cell transcriptomics to identify niche-specific signaling programs in multiple myeloma that drive progression and immunosuppression.

1 citation

humanspatial transcriptomics

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 27, 2023

Interleukin-1 receptor antagonist is a conserved factor for exacerbating tuberculosis susceptibility

Ophelia V. Lee, Enish Pathak, Sujhey Hernández-Bazán…·Dmitri Ivanovich Kotov

The paper identifies IL-1 receptor antagonist as a conserved factor limiting Mtb control across mice, non-human primates, and humans.

9 citations

mousenon-human primate

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GenomicsNature CommunicationsPeer-reviewedApr 23, 2019

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

Benjamin G. Barwick, Paola E. Neri, Nizar Jacques Bahlis…·Lawrence Boise

The paper identifies IgL translocations in multiple myeloma as a marker of poor prognosis, often misclassified as standard risk due to co-occurrence with hyperdiploidy.

147 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky