Author

Huifen Chen

GenentechORCID 0000-0001-8273-9295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

David N. M. JonesiD· 1 shared David Vaisar· 1 shared Guy P. A. VigersiD· 1 shared Jake W. AndersoniD· 1 shared John G. Moffat· 1 shared Laurel M. PegramiD· 1 shared Natalie G. AhniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

David N. M. JonesORCID

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1 paper

Recent·Most cited

BiochemistryeLifePeer-reviewedSep 28, 2023

Conformation Selection by ATP-competitive Inhibitors and Allosteric Communication in ERK2

Jake W. Anderson, David Vaisar, David N. M. Jones…·Natalie G. Ahn

This study identifies 14 ATP-competitive ERK2 inhibitors that select for the R-state conformation, revealing structural changes and allosteric communication mechanisms.

25 citations

experimental assayprotein folding & dynamics

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