Author

Vasundhara Singh

Broad InstituteORCID 0000-0001-8391-8527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aarthee Baskaran· 1 shared Alexandra SchnelliD· 1 shared Allon WagneriD· 1 shared Andreas R. GschwindiD· 1 shared Aviv RegeviD· 1 shared Brandon Schellhaass· 1 shared Chad J. MungeriD· 1 shared Chao WangiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Aarthee Baskaran

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 16, 2025

A systematic survey of distal element-gene regulatory interactions with Direct-Capture Targeted Perturb-seq

Judhajeet Ray, Evelyn Jagoda, Maya U. Sheth…·J Engreitz

The paper identifies distal regulatory element-gene interactions using DC-TAP-seq, finding most have small effect sizes and many are near promoters, highlighting limitations of current predictive models.

5 citations

humanCRISPR screen

𝕏 PostBluesky

GenomicsCellPeer-reviewedJul 2, 2021

In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and Autoimmunity

Allon Wagner, Chao Wang, Johannes Fessler…·Nir Yosef

The paper introduces Compass, an algorithm that uses single-cell RNA-Seq and flux balance analysis to characterize metabolic states in Th17 cells, revealing a metabolic switch and novel anti-inflammatory regulators.

524 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky