BiophysicsJournal of Molecular Graphics and ModellingPeer-reviewed
Computational insights into the conformational transition of STING: mechanistic, energetic considerations, and the influence of crucial mutations
Zhenlu Li, Congran Yue, Shangqiang Xie…·Sheng Ye
This study investigates the conformational transition of STING upon cGAMP binding, identifying mutations that affect the energetic landscape and suggesting V147L may not be a gain-of-function mutation.
2 citations