Author

Jon Haël Brenas

Wellcome Sanger InstituteORCID 0000-0001-9395-9365Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alistair MilesiD· 3 shared Chris S. ClarksoniD· 3 shared Abdoul Azize MillogoiD· 1 shared Abdoulaye DiabatéiD· 1 shared Abdoulaye Sadio· 1 shared Adrien Marie Gaston BélemiD· 1 shared Alfred Amambua‐NgwaiD· 1 shared Anastasia Hernández-KoutouchevaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersGenomics

Alistair MilesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsbioRxivPreprintMay 12, 2026

Genomic signatures of selection in Anopheles funestus reveal shared and population-specific adaptive variation across African populations

Helga D.M. Saizonou, Abdoulaye Sadio, Harouna M Soumaré…·Alfred Amambua‐Ngwa

The paper identifies genomic signatures of selection in Anopheles funestus across African populations, revealing shared and population-specific adaptive variation linked to insecticide resistance and neuromodulatory pathways.

DOI 10.64898/2026.05.07.723524

whole-genome sequencingstatistical model

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Evolutionary BiologyMalaria JournalPeer-reviewedSep 17, 2024

Whole-genome sequencing of major malaria vectors reveals the evolution of new insecticide resistance variants in a longitudinal study in Burkina Faso

Mahamadi Kientega, Chris S. Clarkson, Nouhoun Traoré…·Abdoulaye Diabaté

The paper uses whole-genome sequencing of malaria vectors to track the emergence and spread of new insecticide resistance variants over time in Burkina Faso.

29 citationstop 1%

humanwhole-genome sequencing

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GeneticsProceedings of the Royal Society B Biological SciencesPeer-reviewedSep 1, 2024

Mechanisms of transcriptional regulation in Anopheles gambiae revealed by allele specific expression

Naomi A. Dyer, Eric R. Lucas, Sanjay Curtis Nagi…·Martin J. Donnelly

The paper identifies cis-regulated genes and cis-regulatory modules in Anopheles gambiae associated with insecticide resistance using allele-specific expression and machine learning.

3 citations

bulk RNA-seqmachine learning (classical)

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