A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease
Fu-Chen Yang, Harrison A. Besser, Hye Rin Chun, Megan A. Albertelli, Nielsen Fernandez‐Becker, Bana Jabrì, Chaitan Khosla
This study identifies intestinal CD103+ dendritic cells as key players in TG2-mediated gluten antigen presentation in celiac disease and shows their role in activating T cells and upregulating TG2 activity.
JCI Insight · Aug 28, 2025Peer-reviewedImmunology