Author
University of California, San Francisco
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Heiko Yang, Hanbing Song, Elizabeth Yip…·Franklin W. Huang
Single cell RNA sequencing of bladder cancer subtypes identified a CA125+ cell state linked to aggressive features and TM4SF1 as a therapeutic target.
Beatrice Gini, Whitney Tamaki, Johnny X. Yu…·Trever Grant Bivona
This study uses single-cell lineage tracing and RNAseq to identify pre-existing resistant tumor subclones in lung cancer models and their transcriptional programs, revealing mechanisms of therapy resistance.
Hannah N. W. Weinstein, Kevin Hu, Lisa Fish…·Franklin W. Huang
This study identifies RPL22 as a tumor suppressor in MSI-H cancers that regulates MDM4 splicing and reveals its role in oncogenic pathways.
Beatrice Gini, Philippe Gui, Wei Wu…·Collin M. Blakely
This study shows that CDK4/6 upregulation causes DNA replication stress and genomic instability, leading to resistance to EGFR inhibitors in lung cancer, and suggests combining CDK4/6 and EGFR inhibitors as a treatment.
Jia Zhao, Gefei Wang, Jingsi Ming…·Patricia Kim Phuong Nguyen
Portal integrates large-scale single-cell datasets efficiently and accurately by preserving biological variation across samples, platforms, and species.