Author

Amanda Kathryn Ciardiello

National Institutes of HealthORCID 0000-0001-9463-8168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Carol J. ThieleiD· 1 shared Haiyan LeiiD· 1 shared Jack F. SherniD· 1 shared Jason J HongiD· 1 shared Man XuiD· 1 shared Xiyuan ZhangiD· 1 shared Zhihui LiuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Carol J. ThieleORCID

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1 paper

Recent·Most cited

Cancer BiologyPLoS BiologyPeer-reviewedMar 28, 2024

MYCN driven oncogenesis involves cooperation with WDR5 to activate canonical MYC targets and G9a to repress differentiation genes

Zhihui Liu, Xiyuan Zhang, Man Xu…·Carol J. Thiele

This study shows MYCN drives oncogenesis by cooperating with WDR5 to activate MYC targets and G9a to repress differentiation genes, and targeting both synergistically inhibits neuroblastoma growth.

18 citations

humanChIP-seq

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