Joel Andrews

This study shows that blocking the angiotensin II type 1 receptor reduces gastric cancer metastasis by restoring tight junctions through mechanisms involving KLF4 and TJ protein expression.

This study identifies a trinuclear metal center in PPM1B that facilitates phosphate hydrolysis through direct substrate coordination and water protonation, revealing a novel catalytic mechanism.

This study identifies TRIP12 as a regulator of DNA polymerase β involvement in DNA damage response and repair by controlling its trafficking and chromatin loading.

The paper evaluates WWE and macrodomain proteins as PAR probes in live cells and shows unique PAR dynamics that can modulate the DNA damage response.