Genetic & Genomic MedicineNeurologyPeer-reviewed
Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization study
Marios K. Georgakis, Eric L. Harshfield, Rainer Malik…·Martin Dichgans
This study uses Mendelian randomization to show that genetic predisposition to T2D and hyperglycemia increases risk of ischemic and small vessel stroke, with distinct effects of insulin resistance and beta-cell dysfunction.
142 citationstop 1%