Pierre‐Olivier Lavoie

This study shows that expressing a constitutively active nitrate reductase in Nicotiana benthamiana increases SARS-CoV-2 Spike protein production by reducing leaf senescence and improving nitrogen metabolism.

The paper compares immune responses in Nicotiana benthamiana leaves expressing coronavirus-like particles (CoVLPs) or influenza VLPs, showing overlapping defense responses and demonstrating that Kunitz trypsin inhibitors reduce CoVLP-induced symptoms.

Agrobacterium-mediated expression of influenza virus-like particles induces a unique molecular signature in Nicotiana benthamiana leaf cells.

Agrobacterium-mediated expression of influenza hemagglutinin results in early and transient activation of the unfolded protein response, preventing deleterious effects caused by unresolved endoplasmic reticrium stress.