Anthony Dominic Kelleher

This study examines immune dynamics in lymph nodes after YFV-17D vaccination, identifying robust B and T cell responses and a conserved germinal center program across different vaccines.

The paper shows how SARS-CoV-2 variants, particularly Omicron, evolved proteolytic controls at the Spike furin cleavage site to enhance transmission while reducing lower respiratory tract pathogenicity.

This study investigates how the tuberculosis-associated microenvironment affects HIV-1 persistence by impairing CD8+ T cell-mediated viral control in coinfected individuals.

This paper shows that SARS-CoV-2 Omicron lineages replicate using a specific ACE2 pool that does not complex with TMPRSS2, unlike pre-Omicron variants.

This study tracks SARS-CoV-2 evolution through 33-100 serial passages in vitro, identifying convergent mutations that may confer fitness or transmissibility advantages.

The paper traces the evolution of autoantibodies in HCV-CV patients, revealing convergent somatic mutations and compromised solubility in pathogenic B cells.

The paper shows Omicron SARS-CoV-2 lineages rely on ACE2 without TMPRSS2 complexes for entry, due to changes in the ACE2 Collectrin-Like Domain affecting TMPRSS2 activation.