BiochemistryScience ImmunologyPeer-reviewed
Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion
Yi Sun, Tyler J. Florio, S. K. Gupta…·Nikolaos G. Sgourakis
This paper determines the structure of a peptide-centric Chimeric Antigen Receptor (PC-CAR) complex and identifies structural principles for antigen recognition across multiple HLA allotypes.
21 citations