Cell BiologyCurrent BiologyPeer-reviewed
A TRPV4-dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration
Ernest Iu, Alexander Bogatch, Wenjun Deng…·Sergey V. Plotnikov
The paper identifies a TRPV4-dependent Ca2+ signaling pathway that regulates lamellipodia actin architecture and promotes cell migration through RhoA and formin-mediated actin assembly.
DOI 10.1016/j.cub.2026.01.024