Daniel Lucas Kerr

This paper introduces a semi-permeable capsule for single-cell genome sequencing, enabling uniform coverage and minimal cross-contamination for detecting genomic variants.

This study shows that CDK4/6 upregulation causes DNA replication stress and genomic instability, leading to resistance to EGFR inhibitors in lung cancer, and suggests combining CDK4/6 and EGFR inhibitors as a treatment.

This paper introduces PERCEPTION, a framework using single-cell transcriptomics to predict cancer treatment response and resistance, outperforming bulk expression-based methods in clinical trials.