Author

Lorena Varela

University of KentORCID 0000-0002-0743-9441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Angela Serrano-Sanchez· 1 shared Encarnación Medina‐CarmonaiD· 1 shared Felipe OssaiD· 1 shared Gary S. ThompsoniD· 1 shared Jack Bragg· 1 shared Jose‐Luis Ortega RoldaniD· 1 shared Joseph Cassar· 1 shared Vahitha B. Abdul‐SalamiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Angela Serrano-Sanchez

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJan 19, 2025

Mechanistic Elucidation of CLIC1 Membrane Insertion via Structural and Dynamic Modulation

Joseph Cassar, Angela Serrano-Sanchez, Jack Bragg…·Jose‐Luis Ortega Roldan

This study elucidates the mechanism of CLIC1 membrane insertion through structural and dynamic analysis, revealing Zn2+-induced conformational changes and oligomerization as critical steps.

DOI 10.1101/2025.01.19.633805

humanprotein structure

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