Molecular BiologybioRxivPreprint
Proteolytic dissection of eIF4G reveals the closed-loop mRNP as an architecture for translation repression.
Ryan Johnston, Mollie A. Brekker, Noelle Khalil…·Shawn M. Lyons
The paper shows that eIF4G cleavage products can either rescue or repress translation, revealing the closed-loop mRNP's role in translational silencing rather than initiation.
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