Cell BiologyThe Journal of Cell BiologyPeer-reviewed
An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation
Kai He, Xiaobo Sun, Chuan Chen…·Jinghua Hu
This study identifies CDK6 as a regulator of axoneme polyglutamylation by phosphorylating FIP5, leading to impaired cilia function and ciliopathies, and shows CDK6 inhibitors can restore cilia function.
16 citations