Author

Tiffani Hui

Department of Chemistry, Tufts University, Medford, MA, USA.ORCID 0000-0002-1355-389XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

Matthew D. ShouldersiD· 2 shared Yu‐Shan LiniD· 2 shared Andrew O. GiacomelliiD· 1 shared Anna I. Ponomarenko· 1 shared Bryce E. Ackermann· 1 shared Cheenou Her· 1 shared David R. AmiciiD· 1 shared Francisco J. Sánchez RiveraiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Matthew D. ShouldersORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedJan 1, 2026

Dominant-negative TP53 mutations potentiated by the HSF1-regulatedproteostasis network

Stephanie Halim, Rebecca M. Sebastian, Kristi E. Liivak…·Matthew D. Shoulders

The paper shows that HSF1 activation supports the emergence of cancer-associated p53 mutations by enhancing their fitness under nutlin-3 pressure.

DOI 10.1016/j.molcel.2025.12.013

humanexperimental assay

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BiophysicsbioRxivSep 8, 2023

The Immune-Evasive Proline 283 Substitution in Influenza Nucleoprotein Increases Aggregation Propensity Without Altering the Native Structure

Jimin Yoon, Yu Meng Zhang, Cheenou Her…·Matthew D. Shoulders

The paper investigates how the Pro283 substitution in influenza nucleoprotein affects protein folding and aggregation, revealing it increases aggregation propensity without altering native structure.

DOI 10.1126/sciadv.adl6144

humanprotein structure

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