Author
University of CambridgeORCID 0000-0002-1408-8176Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Daniel H. Jacobson, Dylan Peter McClurg, Yibing Wang…·Lizhe Zhuang
The paper generates organoid models of Barrett oesophagus and oesophageal adenocarcinoma to study disease progression and therapy response.
Piyali Ganguli, Celia De Los Angeles Colomina Basanta, Amelia Acha‐Sagredo…·Jo Spencer
The paper investigates how CDKN2A and other 9p21 gene losses influence oesophageal cancer progression, finding context-dependent effects on survival and immune infiltration.
Yujie Jiang, Matthew D. Montierth, Kaixian Yu…·Wenyi Wang
The paper develops CliPP to estimate subclonal mutation load (sML) and shows it predicts survival and immunotherapy response in cancers with low to moderate TMB.
Fereshteh Izadi, Benjamin P. Sharpe, Stella Panagio Breininger…·Tim Underwood
This study identifies genomic features associated with response to neoadjuvant chemotherapy in esophageal adenocarcinoma, finding lower mutation burden and specific copy number alterations linked to resistance.
Sam Abujudeh, Sebastian S. Zeki, MCV van Lanschot…·Richard Calvin Turkington
The paper introduces conliga, a method for inferring high-resolution SCNA profiles from a low-cost and simple assay, addressing the need for affordable SCNA analysis in clinical settings.