Author

Scott Michael Lippman

UC San Diego Health SystemORCID 0000-0002-1643-4124Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Alvin Wei Tian NgiD· 1 shared Andrea CastroiD· 1 shared Annalise Katz‐SummercorniD· 1 shared Brian J. ReidiD· 1 shared Carissa A. SancheziD· 1 shared Carlo C. MaleyiD· 1 shared Hannah K. CarteriD· 1 shared Hoon KimiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alvin Wei Tian NgORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer Immunology ResearchPeer-reviewedSep 10, 2024

Integrated germline and somatic features reveal divergent immune pathways driving ICB response

Timothy J. Sears, Meghana S. Pagadala, Andrea Castro…·Hannah K. Carter

This paper uses machine learning to predict ICB response by integrating germline and somatic features, revealing differences in immune pathways and clinical outcomes between MHC-I and MHC-II neoantigen reliant tumors.

13 citations

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJul 25, 2022

Extrachromosomal DNA in the cancerous transformation of Barrett's esophagus

Jens Luebeck, Alvin Wei Tian Ng, Patricia C. Galipeau…·Paul S. Mischel

The paper investigates the development and evolution of extrachromosomal DNA (ecDNA) in Barrett's esophagus patients progressing to esophageal adenocarcinoma, finding ecDNA is strongly associated with cancer progression and enriched for oncogenes and immunomodulatory genes.

DOI 10.1101/2022.07.25.501144

humanwhole-genome sequencing

𝕏 PostBluesky