Genetic & Genomic MedicinemedRxivPreprint
Rare coding variation implicates thirteen genes in bipolar disorder across 232,536 individuals from global populations
DOI 10.64898/2026.09.30.26364416
Author
Carlos López‐Jaramillo
Universidad de AntioquiaORCID 0000-0002-1875-1369Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 44 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 shared papersGenetic & Genomic Medicine
Loes M. Olde LoohuisORCID
Mutual co-authors in cluster
8 papers
Recent·Most cited
- Genetic & Genomic MedicinemedRxivPreprint
A founder population reveals genetic variation with major effect on serious mental illness
G. H. Gerdes, Veronica Tozzo, Susan K. Service…·Loes M. Olde Loohuis
The paper identifies a founder variant in ADAP1 associated with increased risk of schizophrenia and bipolar disorder in a Colombian genetic isolate.
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A Scalable Toolkit for Modeling 3D Surface-based Brain Geometry
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The paper introduces a scalable toolkit for 3D surface-based brain analysis, demonstrating its utility in mapping subcortical shape variations across 21 international samples.
DOI 10.1007/978-3-032-06774-6_18 - GenomicsbioRxivPreprint
A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner
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The paper introduces BGE, a sequencing method that combines low-pass whole genome and deep whole exome data, showing high accuracy and cost-effectiveness for genetic variant discovery.
12 citations - NeuroscienceMolecular PsychiatryPeer-reviewed
Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study
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This study investigates how structural brain alterations in schizophrenia relate to network architecture, finding hub susceptibility and shared epicenters across disease stages and disorders.
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Distinct and shared contributions of diagnosis and symptom domains to cognitive performance in a case-control study of severe mental illness in the Paisa population
Susan K. Service, Cristian Vargas Upeguí, Mauricio Castaño Ramírez…·Nelson B. Freimer
The paper investigates how diagnosis and symptom domains affect cognitive performance in a case-control study of severe mental illness, finding distinct cognitive profiles linked to specific symptom domains.
36 citations - GeneticsTranslational PsychiatryPeer-reviewed
Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates
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This study examines genetic risk for bipolar disorder in extended families, finding that both common and rare variants contribute to susceptibility, with no significant segregation of large-effect variants.
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The paper analyzes genomic diversity in Latin American population isolates, finding increased genetic diversity and consanguinity compared to the Finnish isolate.
63 citations