Author

Ruchi Sharma

National Institutes of HealthORCID 0000-0002-2138-6462Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ruchi Sharma2 papers · Babraham Institute

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Kapil BhartiiD· 2 shared Ahmed H. GhobashiiD· 1 shared Ajith V. PankajamiD· 1 shared Alexandra–Chloé VillaniiD· 1 shared Ana-Cristina Almansa-GarciaiD· 1 shared Angela ArmentoiD· 1 shared Anjun MaiD· 1 shared Berta de la CerdaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Kapil BhartiORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 24, 2026

An Integrated Multi-omics Single Cell Atlas of the Human RPE and Choroid

Jianming Shao, Xuan Bao, Ismail Yaman…·Rui Chen

The paper constructs a multi-omics single-cell atlas of human RPE and choroid, identifying cell types, aging patterns, and genetic risk factors for AMD.

1 citation

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Cell BiologyFrontiers in ImmunologyPeer-reviewedFeb 6, 2025

The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells

Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia…·Marius Ueffing

This study shows that the CFH Y402H polymorphism increases vulnerability of iPSC-RPE cells to Hydroquinone-induced oxidative stress, suggesting genetic risk predisposition rather than soluble FH effects.

10 citationstop 2%

humanbulk RNA-seq

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