Molecular BiologybioRxiv
Single-cell Rapid Capture Hybridization sequencing (scRaCH-seq) to reliably detect isoform usage and coding mutations in targeted genes at a single-cell level
Hongke Peng, Jafar S. Jabbari, Luyi Tian…·Rachel Thijssen
The paper introduces scRaCH-seq, a method for single-cell long-read sequencing that improves detection of isoform usage and mutations in targeted genes, demonstrating its application in CLL samples.
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