Author

Cristina Escrevente

Universidade Nova de LisboaORCID 0000-0002-2183-3947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Miguel C. SeabraiD· 2 shared Ana S. FalcãoiD· 1 shared Duarte C. BarraliD· 1 shared Inês Paz SantosiD· 1 shared Inês S. FerreiraiD· 1 shared João CharnecaiD· 1 shared Mafalda Lopes‐da‐SilvaiD· 1 shared Margarida Pedro· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Miguel C. SeabraORCID

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2 papers

Recent·Most cited

Cell BiologyJournal of Investigative DermatologyPeer-reviewedSep 19, 2024

Photoprotective melanin is maintained within keratinocytes in a storage lysosome

Matilde V. Neto, Michael J. Hall, João Charneca…·Duarte C. Barral

The paper shows melanin-containing phagosomes in keratinocytes mature into storage lysosomes called melanokerasomes, which retain melanin for long-term photoprotection.

21 citations

humanimaging

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Molecular BiologybioRxivPreprintSep 17, 2024

Enhancing lysosome function via mTOR/TFEB activation reduces lipofuscin-like granules in early Age-related Macular Degeneration

Ana S. Falcão, Mafalda Lopes‐da‐Silva, Pedro Antas…·Miguel C. Seabra

This study shows that activating the mTOR/TFEB pathway reduces lipofuscin-like granules in AMD by improving lysosomal function and POS digestion.

1 citation

humanbulk RNA-seq

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