Genetic & Genomic MedicinemedRxivPreprint
Deciphering causal proteins in Alzheimer's disease: A novel Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction
Minhao Yao, Gary Wright Miller, Badri Narayan Vardarajan…·Zhonghua Liu
The paper develops MR-SPI, a Mendelian randomization method integrated with AlphaFold3 to identify causal protein biomarkers and predict 3D structural changes in Alzheimer's disease.
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