Andrew R. Nager

The paper identifies SLK as a cancer-specific co-regulator of c-Myc using photoproximity labeling, showing it stabilizes c-Myc and drives tumorigenesis through splicing changes.

This paper identifies an acetylation-dependent circuit controlling SEC integrity in AML, showing that disrupting KAT2A/B leads to broad anti-leukemic effects across subtypes.

The paper uses covalent probes and paralog hopping to identify ligandable pockets in proteins lacking cysteines, demonstrating a method to expand the ligandable proteome.