Author
Massachusetts General HospitalORCID 0000-0002-3073-625XUnclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Jonathan G. Van Vranken, Jiaming Li, Julian Mintseris…·Devin K. Schweppe
This study uses proteome-wide thermal shift assays to analyze over a million thermal stability measurements from 96 compounds in cells and 70 in lysates, revealing target engagement and off-target effects.
Junbing Zhang, Claire M. Simpson, Jacqueline Berner…·Liron Bar‐Peled
The paper identifies a nucleus-to-mitochondria ROS sensing pathway involving CHK1 and SSBP1 that mediates resistance to platinum-based chemotherapies in ovarian cancers.
Tommy Weiss‐Sadan, Maolin Ge, Makiko Hayashi…·Liron Bar‐Peled
The paper shows NRF2 activation in KEAP1 wildtype lung cancers causes NADH-reductive stress, making them vulnerable to Complex I inhibition.