PhysiologyeLifePeer-reviewed
A 2-Hydroxybutyrate-mediated feedback loop regulates muscular fatigue
Brennan J. Wadsworth, Marina Leiwe, Eleanor A Minogue…·Randall S. Johnson
This study shows that 2-hydroxybutyrate (2HB) produced during exercise inhibits branched-chain aminotransferases, leading to metabolic changes that enhance oxidative capacity.
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