Bridget M. Barker

Proteome-wide discovery of novel diagnostic antigens for coccidioidomycosis

This study identifies novel diagnostic antigens for coccidioidomycosis using high-dimensional peptide serology, showing improved accuracy in distinguishing infected individuals from controls.

Genome variation of Sporothrix schenckii and Sporothrix brasiliensis

The paper analyzes genome variation in Sporothrix species to understand their evolutionary strategies and drug resistance mechanisms.

A Novel Sarocladium spinificis Strain Suppresses Coccidioides posadasii Growth: Morphological and Genetic Perspectives

This study characterizes two clinical Sarocladium spinificis strains that inhibit Coccidioides posadasii growth, revealing their genomic features and potential antifungal properties.

Inferring the composition of a mixed culture of natural microbial isolates by deep sequencing

The paper develops a method to infer strain composition in microbial mixed cultures using natural SNPs as barcodes, validated on Coccidioides posadasii isolates and applied to GWAS.

Using double cut in vitro assembled CRISPR/Cas9 to modify the genome of Coccidioides posadasii

The paper identifies a defensin-like gene in Coccidioides posadasii with high transcript levels in spherules and uses CRISPR-Cas9 to delete it.

A chromosomal-level reference genome of the widely utilized Coccidioides posadasii laboratory strain "Silveira"

The paper presents a chromosomal-level genome assembly of the Coccidioides posadasii Silveira strain using SMRT sequencing, improving genome annotation and enabling future genomic studies.

Structural characterization and evolutionary analyses of the Coccidioides immitis and Coccidioides posadasii mitochondrial genomes

The paper assembles and annotates mitochondrial genomes of Coccidioides immitis and C. posadasii, and assesses population variation across 77 genomes, identifying common genes and introns.