Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22
Fangtao Chi, Qiming Zhang, Jessica E.S. Shay…·Ömer H. Yilmaz
This study shows that dietary cysteine improves intestinal stem cell repair through IL-22 from CD8+ T cells.
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Dana-Farber Cancer InstituteORCID 0000-0002-3576-3169Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Fangtao Chi, Qiming Zhang, Jessica E.S. Shay…·Ömer H. Yilmaz
This study shows that dietary cysteine improves intestinal stem cell repair through IL-22 from CD8+ T cells.
Abigail A. Jaquish, Eleni Phung, Xutong Gong…·Deepshika Ramanan
The paper examines T cell changes in mammary glands during pregnancy and lactation, finding an expansion of T effector cells and similarities to intestinal T cells.
Tanjina Kader, Jia‐Ren Lin, Clemens B. Hug…·Sandro Santagata
This study uses spatial profiling to show immune suppression and microenvironment changes in fallopian tube precursors of high-grade serous ovarian cancer.
Kenichi Shimada, Daniel E. Michaud, Yvonne Xiaoyong Cui…·Jennifer L. Guerriero
This study identifies an estrogen receptor signaling program in HR+ breast cancer that suppresses immune responses by reducing T cell infiltration and HLA expression, suggesting therapeutic targets to enhance immunogenicity.