Author
Universitair Ziekenhuis LeuvenORCID 0000-0002-3604-7850Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Alexandra Pančíková, Ruben Cools, Marios Eftychiou…·Jonas Demeulemeester
SPLONGGET enables comprehensive genotype-phenotype analysis by integrating long-read single-cell genome, transcriptome, and open chromatin profiling in thousands of cells.
Alexandra Bacquelaine Veloso, Thomas Slegers, Jente M. Schoenaker…·Marlies Vanden Bempt
This study shows that targeting EZH2 and HDACs together induces ferroptosis in hematological malignancies by upregulating cholesterol biosynthesis and causing metabolic stress.
Charlien Vandersmissen, Sofie Demeyer, Kris Jacobs…·Jan Cools
The paper identifies PSEN1 mutations that confer resistance to MRK-560 in T-ALL, revealing three distinct resistance mechanisms.