Author

Yan Feng

Shanghai Jiao Tong UniversityORCID 0000-0002-3742-5972Unclaimed ORCID profile · follow to get notified of new preprints

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Yan Feng2 papers · State Key Laboratory for Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:graph neural network· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Approach:transformer / foundation model· 1

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Abdul WadoodiD· 1 shared Bo ZhangiD· 1 shared Haifeng CheniD· 1 shared Jamshed IqbaliD· 1 shared Junxi MuiD· 1 shared Qi Zhang· 1 shared Ting WeiiD· 1 shared Zhengxin LiiD· 1 shared

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2024-2024 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Abdul WadoodORCID

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1 paper

Recent·Most cited

BiochemistryBriefings in BioinformaticsPeer-reviewedMar 12, 2024

De novo Protein Sequence Design Based on Deep Learning and Validation on CalB Hydrolase

Junxi Mu, Zhengxin Li, Bo Zhang…·Haifeng Chen

The paper designs novel protein sequences using a Graphormer-based model and validates them on CalB hydrolase, achieving 1.7x higher specific activity than the wild type.

19 citations

protein sequencedeep learning

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