Author

Yuan‐Wei Zhang

Guangzhou UniversityORCID 0000-0002-4276-9251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Eva HellsbergiD· 2 shared Gary RudnickiD· 2 shared Lucy R. ForrestiD· 2 shared Qingyang CheniD· 2 shared Angela BäckeriD· 1 shared Bethlehem BekeleiD· 1 shared Chan LiiD· 1 shared Chuntong YiniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBiochemistry

Eva HellsbergORCID

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3 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedAug 24, 2026

The Role of Chloride Ions in Serotonin Transport

Jiahui Huang, Angela Bäcker, Stacy Uchendu…·Lucy R. Forrest

This study investigates the role of chloride ions in serotonin transport, showing they do not drive uptake but stabilize transporter conformations by enhancing sodium binding and helix packing.

DOI 10.1073/pnas.2605760123

humanbiophysical modeling

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 16, 2026

High glucose confers senescence resistance via GLUT1 epigenetic rewiring to blunt immunotherapy responses in esophageal squamous cell carcinoma

Jinxiu Dong, Jie Zhou, Jia‐Jie Hao…·Yan‐Yi Jiang

This study identifies GLUT1 as a driver of immunotherapy resistance in ESCC by epigenetically suppressing senescence and reveals dietary glucose restriction as a potential strategy to enhance immunotherapy efficacy.

DOI 10.64898/2026.07.15.738372

humanbulk RNA-seq

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BiochemistryProceedings of the National Academy of SciencesPeer-reviewedApr 23, 2024

Identification of the potassium binding site in serotonin transporter SERT

Eva Hellsberg, Danila Boytsov, Qingyang Chen…·Lucy R. Forrest

This study identifies the Na2 site as the potassium binding site in SERT using molecular dynamics simulations and site-directed mutagenesis.

11 citations

humanproteomics

𝕏 PostBluesky