Cell BiologybioRxivPreprint
5-ethynyluridine perturbs nuclear RNA metabolism to promote the nuclear accumulation of TDP-43 and other RNA binding proteins
Lindsey R. Hayes, Benjamin L. Zaepfel, Lauren Duan…·Petr Kaláb
This study shows that 5-ethynyluridine (5EU) causes nuclear accumulation of TDP-43 and other RNA-binding proteins by altering RNA metabolism and splicing.
DOI 10.1101/2025.04.02.646885