Author

Sabrina Chan

Harvard UniversityORCID 0000-0002-4557-2972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Peter Karl SorgeriD· 3 shared Sandro SantagataiD· 3 shared Shannon CoyiD· 3 shared Clarence YappiD· 2 shared Ino de BruijniD· 2 shared Jeremy L. MuhlichiD· 2 shared Jong Suk LeeiD· 2 shared Juliann B. TefftiD· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Peter Karl SorgerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedDec 20, 2024

Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma

Tanjina Kader, Jia‐Ren Lin, Clemens B. Hug…·Sandro Santagata

This study uses spatial profiling to show immune suppression and microenvironment changes in fallopian tube precursors of high-grade serous ovarian cancer.

60 citationstop 1%

humanspatial transcriptomics

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Cancer BiologybioRxivPreprintSep 24, 2024

Integrating spatial profiles and cancer genomics to identify immune-infiltrated mismatch repair proficient colorectal cancers

Jeremiah A. Wala, Ino de Bruijn, Shannon Coy…·Peter Karl Sorger

The paper identifies a subset of mismatch repair proficient colorectal cancers with high immune infiltration that may benefit from immune checkpoint inhibitors, using spatial profiling and genomics.

5 citations

humanspatial transcriptomics

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Cancer BiologybioRxivPreprintNov 7, 2023

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee…·Sandro Santagata

The paper shows nuclear rupture is common in cancer, especially glioblastoma, and links it to lamin proteins and immune signaling.

11 citations

humanimaging

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