Author

Peiran B Yang

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-4635-1215Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Physiology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Organism:rat· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Paul B. YuiD· 2 shared Ana Zeghibe· 1 shared Bolun LiiD· 1 shared Chaosheng DengiD· 1 shared Christine Huard· 1 shared Dawen WuiD· 1 shared Elizabeth Shin· 1 shared Erik Martı́nez-HackertiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersPhysiology

Paul B. YuORCID

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Author profile →

3 papers

Recent·Most cited

BMP9 regulates the endothelial secretome to drive pulmonary hypertension

Ying Zhong, Peiran B Yang, Luca Troncone, Oleg V. Kovalenko, Eva Maria Fast, Shreyas Rajesh, Sydney Lavoie, Kathleen E. Tumelty, Elizabeth Shin, Taylor A. Covington, Ana Zeghibe, Marc H. Wadsworth, Stephen M. Christensen, Robin S. Nathans, Susan Benard, , Paul B. Yu

This study shows that inhibiting BMP9 signaling reduces endothelial secretion of vasoactive factors that drive pulmonary vascular remodeling in pulmonary hypertension.

bioRxiv · Aug 29, 2025 · PreprintPhysiology

Cross-species analysis of experimental PH at single cell resolution reveals prominent contributions Ednrb+ EC and Dhcr24+ macrophage populations

Bolun Li, Yanjiang Xing, Yitian Zhou, Xingqi Xiao, Ting Shu, Xiaomin Song, Hongmei Zhao, Xiao-Jian Wang, Junling Pang, Peiran B Yang, Paul B. Yu, Jing Wang, Wang Chen

The paper integrates cross-species single-cell data from rodent PH models and human disease to identify overlapping cell subsets and novel macrophage and endothelial subtypes involved in PH.

bioRxiv · Apr 30, 2025 · PreprintBioinformatics

Construction of Animal Models Based on Exploring Pathological Features and Mechanisms of Different Locations in the Progression of DVT-APTE-CTEPD/CTEPH

Qinghuang Lin, Wenfeng Wang, Xiaoyun Chen, Jixiang Liu, Nan Shao, Qiuxia Wu, Xingyue Lai, Maohe Chen, Min Chen, Yijin Wu, Dawen Wu, Hongli Li, Peiran B Yang, Yunxia Zhang, Zhu Zhang, , Chaosheng Deng

This study constructs animal models to simulate different stages of DVT-APTE-CTEPD/CTEPH progression and compares their effectiveness in capturing pathological features.

bioRxiv · Mar 28, 2024 · PreprintZoology