Author

Ramakrishnan Rajagopalan

Children's Hospital of PhiladelphiaORCID 0000-0002-5028-1010Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ramakrishnan Rajagopalan2 papers · Children's Hospital of Philadelphia

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Andrew S. AlleniD· 1 shared Christopher J. SottolanoiD· 1 shared Constantine StavrianidisiD· 1 shared Grace E. RhodesiD· 1 shared Grace Tzun-Wen ShawiD· 1 shared Tanaya JadhaviD· 1 shared Tristan J. HayeckiD· 1 shared Yuncheng DuaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

Andrew S. AllenORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Evolutionary BiologybioRxivPreprintSep 24, 2025

Functional Category-Specific Intolerance Reflects Genic Function and Clinical Relevance

Yuncheng Duan, Constantine Stavrianidis, Grace Tzun-Wen Shaw…·Andrew S. Allen

This paper introduces CATMINT, a method to estimate gene-level intolerance across variant categories, showing it outperforms existing metrics and reveals category-specific intolerance patterns in disease genes.

DOI 10.1101/2025.09.24.678298

humanwhole-genome sequencing

𝕏 PostBluesky