Gene therapy targeting of AKAP6β-CaMKII signalosomes improves myocardial inflammation and heart failure in a swine model of cardiometabolic syndrome
Darla L. Tharp, Sofia M. Possidento, Jinliang Li…·Michael S. Kapiloff
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Cedars-Sinai Medical CenterORCID 0000-0002-5055-4875Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Darla L. Tharp, Sofia M. Possidento, Jinliang Li…·Michael S. Kapiloff
Qin Fu, Philip M. Remes, Jihyeon Lee…·Jennifer E. Van Eyk
The paper develops and evaluates a multiplexed PRM-MS assay for quantifying plasma proteins in an IBD cohort, demonstrating high quantifiability and consistent data acquisition.
Qin Fu, Manasa Vegesna, Niveda Sundararaman…·Jennifer E. Van Eyk
This paper introduces TEAQ, a software tool that selects clinical-grade biomarker candidates from DIA-MS data by evaluating protein quantification metrics in a discovery cohort.
Giorgi Margvelani, Justin Ralph Welden, Karol Andrea Arizaca Maquera…·Stefan Stamm
This study shows that FTDP-17 mutations affect circTau RNA formation and translation, with ADAR1-p150 editing playing a key role in their expression and function.