ImmunologyAmerican Journal of Physiology-Cell PhysiologyPeer-reviewed
Mast-Cell Expressed Membrane Protein-1 (MCEMP1) is expressed in classical monocytes and alveolar macrophages in Idiopathic Pulmonary Fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ dependent manner.
Carole Y. Perrot, Τheodoros Karampitsakos, Avraham Unterman…·Jose D. Herazo‐Maya
This study identifies MCEMP1 as highly expressed in monocytes and macrophages in IPF, regulated by TGFβ and involved in chemotaxis, adhesion, and migration through RHO GTPase modulation.
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