Author

Russell Ault

Children's Hospital of PhiladelphiaORCID 0000-0002-5430-5366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

David A. BakeriD· 2 shared Dionne K. VafeadosiD· 2 shared Amir MotmaeniD· 1 shared Andrew J. BorstiD· 1 shared Armita NourmohammadiD· 1 shared Basile I. M. WickyiD· 1 shared Benedikt SingeriD· 1 shared Bingxu LiuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

David A. BakerORCID

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2 papers

Recent·Most cited

BioengineeringNaturePeer-reviewedNov 5, 2025

Atomically accurate de novo design of antibodies with RFdiffusion

Nathaniel R. Bennett, Joseph L. Watson, Robert J. Ragotte…·David A. Baker

This paper designs antibodies de novo with atomic precision using RFdiffusion and yeast display, validated by cryo-EM and biophysical methods.

381 citationstop 1%

protein structuredeep learning

𝕏 PostBluesky

ImmunologySciencePeer-reviewedJul 24, 2025

Design of high specificity binders for peptide-MHC-I complexes

Bingxu Liu, Nathan F. Greenwood, Julia E. Bonzanini…·David A. Baker

The paper designs high specificity binders for peptide-MHC-I complexes using deep learning, achieving specific targeting of pMHCs and enabling T-cell activation.

88 citationstop 1%

protein structuredeep learning

𝕏 PostBluesky