Author

Siamak Amirfakhri

University of California San DiegoORCID 0000-0002-5534-1043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Michael BouvetiD· 2 shared Adel Adel· 1 shared Annelies Ondersma· 1 shared Celia R. Espinoza· 1 shared Christopher W. BenneriD· 1 shared Courtney TindleiD· 1 shared Eleadah Vidales· 1 shared Ella McLareniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Michael BouvetORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 14, 2025

Gastric cancer treatment target identified from an accelerated Helicobacter-induced gastric cancer mouse model

Emma Mathilde Kurstjens, Kristin E. Cox, Prerna Bali…·Marygorret Obonyo

The paper identifies PSMB8 as a potential therapeutic target in gastric cancer and shows carfilzomib's efficacy in reducing tumor growth and inducing apoptosis in a mouse model.

DOI 10.1101/2025.06.14.659641

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 13, 2023

Machine Learning Guided Differentiation Therapy Targets Cancer Stem Cells in Colorectal Cancers

Saptarshi Sinha, Joshua Alcantara, Kevin Perry…·Pradipta Ghosh

This paper introduces a machine learning framework to identify and target transcriptomic vulnerabilities in colorectal cancer, demonstrating that differentiation therapy selectively eliminates cancer stem cells and reduces recurrence risk.

DOI 10.1101/2023.09.13.557628

humanbulk RNA-seq

𝕏 PostBluesky