GenomicsCellPeer-reviewed
Cohesin Loss Eliminates All Loop Domains, Leading To Links Among Superenhancers And Downregulation Of Nearby Genes
Suhas S.P. Rao, Su-Chen Eileen Huang, Brian Glenn St Hilaire…·Erez Lieberman Aiden
This study shows that cohesin loss eliminates loop domains, causing superenhancer links and gene downregulation, which are reversible upon cohesin restoration.
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