Molecular BiologybioRxivPreprint
Chemical and genetic screens identify new regulators of tetracycline-inducible gene expression system in mammalian cells
Valeria Colicchia, Maria Häggblad, Oleksandra Sirozh…·Óscar Fernández-Capetillo
The paper identifies chemical and genetic regulators of the tetracycline-inducible gene expression system in mammalian cells, showing that FDA-approved drugs and genetic modifiers inhibit the system rather than alleviate TDP-43 toxicity.
DOI 10.1101/2022.03.16.484587